Realizing RNA Fragmentomics
We're discovering new biomarkers to advance next-generation diagnostics that provide deeper insights and improve more lives.
RiboMarker®: The Platform for RNA Biomarker Discovery
Our proprietary RiboMarker® platform uncovers novel biomarkers by analyzing RNA fragments that other approaches cannot detect through a combination of library construction, NGS, and AI-powered bioinformatics tools. RiboMarker’s enabling technology unlocks next-generation RNA analytes for broad diagnostic applications from liquid biopsies for oncology or infectious disease, to soil sampling.
Why RNA Fragmentomics?
If you’re missing RNA fragments, you’re missing RNA’s potential.
Complete Transcriptomics
RNA fragments hold dynamic biological information that is missed by traditional techniques. Analyzing RNA fragments provides rich insights into the transcriptome such as the progression of a disease, rather than simply its presence or absence.
Broad Diagnostic Applicability
Current techniques only see about 10% of RNA. Our RiboMarker platform can see the other 90%. Unlocking the ability to detect and analyze RNA fragments from virtually any biological sample means deeper insights and better diagnostics that ultimately help people live happier and healthier lives.
Complementary Analysis
While DNA analysis is ubiquitous in liquid biopsies and many diagnostic applications due to its ease-of-use, RNA fragmentomics is a powerful complementary technique that provides greater insight and accuracy than DNA analysis alone is capable of.
RNA NGS Products and Services
We offer a wide range of sequencing services and library preparation from extracted RNA or ready-to-sequence pooled libraries to customized products for your bioinformatic needs. We also provide library preparation kits available for online purchase or via PO.
Complete Small RNA library preparation kit for Illumina for RNA samples from biofluids and other low concentration samples. Patented technology with a single-adapter and circularization to reduce detection bias. For RNA samples extracted from biofluid samples and other sample types with low RNA concentration. Indexes are added using a single index. Each 48 reaction kit includes 48 unique barcodes. Each 12 reaction kit includes 12 unique barcodes.
Size selection reagent and barcoded PCR primers are included.
Complete Small RNA library preparation kit for Illumina for RNA samples from tissues or cells. Patented technology with a single-adapter and circularization to reduce detection bias. For total RNA samples from tissue or cells (1 ng to 1000 ng total RNA input). Indexes are added using a single index. Each 48 reaction kit includes 48 unique barcodes. Each 12 reaction kit includes 12 unique barcodes.
Size selection reagent and barcoded PCR primers are included.
Complete Small RNA library preparation kit for Illumina for RNA samples from tissues, cells, or biofluids. Patented technology with a single-adapter and circularization added capability of using dual barcoding. Indexes are added using a combinatorial dual index. Each 48 reaction kit includes 48 unique barcode combinations, with up to 384 unique combinations possible for multiplexing.
Size selection reagent and barcoded PCR primers are included.
For 12 reaction kits: please select which 1 out of 8 forward primers (FP) and set of 12 reverse primers you want included in your kit.
For 48 reaction kits: please select reverse primer set 1-48. Each kit includes all 8 forward primers.
Our Latest News and Insights
Keep up with the most recent company updates and our expert insights on RNA fragmentomics.
Ready to Help Realize RNA Fragmentomics?
We were founded on NIH funding and we are determined to bring the benefits of RNA fragmentomics to the world.
We are actively seeking collaboration with industry or research partners to correlate the rapidly growing wealth of novel RNA biomarkers with clinical outcomes.
